Miami Keratokonus Cross Linking Treatment (CXL) Corneal collagen cross-linking is a technique that was first used in 1998 to treat patients with a disease called keratoconus. In keratoconus, the cornea (the front clear window of the eye) becomes weak, thin, and irregularly shaped. Miamikeratoconus.com~Site InfoWhoisTrace RouteRBL Check