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Osteonecrosis of the jaw (ONJ) is a Zometa drug side effects condition in which part of the jaw bone is no longer alive and cannot regenerate itself due to a lack of blood supply. Most commonly in the past, patients developed ONJ after bone trauma, such as a tooth extraction. Rather than healing, the bone begins to die. In some cases, the bone becomes exposed, which can lead to serious infection and fracture. In extreme cases, surgery is required to remove the dead bone.
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