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Bcl-2
Find information on Bcl-2. Your source for information on Bcl-2 Genes and Proteins, and their role in Apoptosis and the Apoptotic Pathway and Disease. Bcl-2 denotes a family of genes and proteins found in mammals which control the outer membrane premeability of mitochondria, and most importantly the fate of the cell through programmed cell death, apoptosis.
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Tumor Suppressor
Find information on Tumor Suppressor Genes and Proteins: APC, BRCA, CDKN2A, DCC, DPC4, E-cadherin, INK4a, KLF6, LKB1, MEN1, MSH2, NF-1, NF-2, p14ARF, p16, p53, PTCH, PTEN, Retinoblastoma, SMAD4, TGF-beta, TSC, VHL and WT-1.
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TP53
TP53.org is a site dedicated to bringing basic, advanced and current information on the TP53 gene, p53 protein and there significance. p53 has revolutionized our understanding of the molecular biology of cancer, cancer initiation and cancer progression. The p53 gene is altered in more than half of all cancers, and its dysfunction is associated with more aggressive cancers and a worse prognosis.
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